BIOM 3200 Chapter Notes - Chapter Unit 2: Inhibitory Postsynaptic Potential, Excitatory Postsynaptic Potential, Muscarinic Acetylcholine Receptor

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180-201, 359-397 do not read 12. 3 and 12. 4. 2. 01 differentiate between a chemical and electrical synapse. Electrical synapse cardiac muscle (myocardium) and smooth muscles (labour contractions), also in many regions of the brain but not very well understood: action potentials are directly conducted from one cell to the next--somewhat. Chemical synapse: the presynaptic nerve endings release chemicals called neurotransmitters which change the membrane potential of the postsynaptic cell, thereby producing action potentials if a threshold depolarization is achieved. 2. 02 identify different neuronal connections including: axodendritic, axosomatic, and axoaxonic. The terminal boutons are separated from the post synaptic cell by a synaptic cleft (10nm) that can only be seen with an em. Cell-adhesion molecules protrude from pre and post synaptic membranes into the synaptic cleft and bond to each other to ensure the membranes stay in close proximity (velcro like effect between cams). Neurotransmitter molecules within the presynaptic neuron endings are contained within many small, membrane-enclosed synaptic vesicles.

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