PATH 3610 Chapter Notes - Chapter 7: Pap Test, Cytostasis, Polycythemia

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Neoplasia: an abnormality in cellular differentiation, maturation, and control of growth it can be considered excessive and disorganized cell or tissue growth that is unresponsive to normal growth control mechanisms. The result of these abnormalities is the development of a tumour or neoplasm, a mass of abnormal tissue. Normal cell growth and differentiation: for the normal structure of tissue to be maintained, the rate of cell proliferation must balance with the rate of differentiation (leading toc ell death). If there is a discrepancy between these rates, then the tissue will become abnormal, both at the gross and histological level. Hormonal hyperplasia proliferation of the glandular epithelium of the female breast at puberty and during pregnancy. Compensatory hyperplasia: residual tissue grows after removal or loss of part of an organism. Most forms of pathological hyperplasia result from excessive hormonal growth or growth factor stimulation.

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