BIOL130 Chapter Notes - Chapter 7: Sigma Factor, Ribonucleotide, Dna Replication
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10 Dec 2016
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From dna to protein: how cells read the genome. Transcription and translation > genetic instructions are expressed out. Genes can be expressed with different efficiencies. Portions of dna sequence are transcribed into rna. First step > copy the nucleotide sequence of that gene into rna > transcription. Rna is a linear polymer made of four different types of nucleotide subunits linked together by phosphodiester bonds. Differs from dna: 1) the nucleotides in rna are ribonucleotides > contain sugar ribose rather than deoxyribose; 2) rna contains uracil instead of thymine. Rna is single-stranded > can fold up into different shapes. Chemical structure-wise, rna contains an additional -oh group. Transcription produces rna complementary to one strand of dna. All the rna in a cell is made by transcription. A) rna contains the sugar ribose, which differs from deoxyribose, the sugar used in. Dna, by the presence of an additional -oh group.
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Related Questions
QUESTION 1. Compared to eukaryotic genomes, only prokaryotic genomes:
A. contain DNA organized by histones. |
B. contain usually one, circular chromosome. |
C. contain plasmid DNA. |
D. have chromosomes contained in a nucleus. |
QUESTION 2. Azathioprine is a drug that may be prescribed to transplant recipients to reduce the chance of tissue rejection reactions. In its active state, it acts as a purine analogue, inhibiting DNA biosynthesis. This means that 6-mercaptopurine will be inserted in place of a purine containing nucleotides during DNA replication. Given this drug's mode of action, you would expect it to be incorporated into DNA in place of:
A. nucleotides containing guanine or cytosine. |
B. nucleotides containing adenine or thymine. |
C nucleotides containing adenine or guanine. |
D. nucleotides containing guanine nucleotide or uracil. |
QUESTION 3. RNA is distinguished from DNA because only RNA:
A. typically exists as a single-stranded molecule. |
B. has a 3' to 5' directionality. |
C. is composed of nucleotides that contain the sugar deoxyribose. |
D. is composed of nucleotides that contain the nitrogen bases T, C, G, and A. |
QUESTION 4. How are RNA nucleotides different from DNA nucleotides? To be marked correct, you'll need to select all true statements, as there may be more than one correct answer.
A. RNA nucleotides do not contain thymine. |
B. RNA nucleotides use the sugar ribose, while DNA nucleotides do not. |
C. RNA nucleotides lack phosphate. |
D. RNA nucleotides incorporate pyrimidine nitrogen bases, while DNA nucleotides only incorporate purine nitrogen bases. |