BIOL373 Chapter : Unit 7 - Metabolism and Energy Balance - Full Textbook Notes
5 Sep 2013
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Satiety centre: stops food intake by inhibiting feeding centre. Glucostatic theory: glucose metabolism by hypothalamic centers regulates food intake. When blood glucose concentrations decrease the satiety centre is suppressed and the feeding centre is dominant. When the glucose metabolism increases the satiety center inhibits the feeding center. Lipostatic theory: a signal from the body"s fat stores to the brain modulates eating behaviour so the body maintains a particular weight. If fat stores are increased then eating decreases. Obesity is caused from a disruption in this pathway. Leptin: protein hormone synthesized in adipocytes under control of ob (obese) gene; acts as negative feedback signal between adipose tissue and brain (increase in fat stores adipose cells secrete lepin food intake decreases). Neuropeptide y (npy): brain neurotransmitter, stimulus for food intake. Ghrelin: peptide secreted by stomach during fasting and increases hunger. Cck and glp-1: released by gut during a meal to help decrease hunger. Psychological factors that regulate food intake: stress; anorexia nervosa.
