BIOL 112 Chapter Notes - Chapter 4, 19: Lactose Permease, Lac Operon, Trp Operon
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BIOL 112 Full Course Notes
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The regulation of gene expression occurs through a hierarchy of regulatory mechanisms acting at different levels from dna to protein. Gene regulation in prokaryotes is simpler than gene regulation in eukaryotes. Transcription and translation are not separated by a nuclear envelope. Expression of a protein-coding gene entails transcription of the gene into messenger rna and translation of the messenger rna into protein. Positive regulation a regulatory molecule (usually a protein) must bind to dna at a site near the gene in order for transcription to take place. Negative regulation a regulatory molecule (usually a protein) must bind to the dna at a site near the gene in order for transcription to be prevented e. g. lac operon and trp operon. Dna, rna polymerase complex, and a regulatory protein called transcriptional activator (increases activity of enzyme) When the activator protein is present in a state that can interact with its binding site in the.