BIOL 112 Chapter Notes - Chapter 7.3, 7.4: Intermembrane Space, Inner Membrane, Pyruvic Acid

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30 Nov 2016
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BIOL 112 Full Course Notes
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Pyruvate is oxidized in the mitochondrial matrix, forming acetyl-coa, the first substrate in the citric acid cycle. A key step that links glycolysis to the citric acid cycle. First process that takes place inside the mitochondria (matrix) A mitochondrion consists of an outer membrane, intermembrane space, inner membrane, and the matrix. Intermembrane space the space between the inner and outer membranes. Mitochondrial matrix the space enclosed by the inner membrane. Overall, the synthesis of one molecule of acetyl-coa from pyruvate results in the formation of one molecule of carbon dioxide and one molecule of nadh. Since a single molecule of glucose forms two molecules of pyruvate during glycolysis, pyruvate oxidation of both pyruvate molecules produces: Oxaloacetate is the starting and ending molecule of the cycle. Inputs and outputs of the cycle: two carbons are eliminated during the cycle, released as carbon dioxide (sources of the carbon dioxide that we exhale when we breathe)

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