PCTH 201 Chapter Notes - Chapter 21: Plasma Protein Binding, Monoamine Oxidase Inhibitor, Cyclic Guanosine Monophosphate
26 Nov 2017
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Fda has approved more than 1500 drugs with many mechanisms. Polypharmacy: takes more than 5 medications (increases risk of drug interaction) 20-30% people that go to emergency is because of this adverse drug reactions. Can be withdrawn from market when discovered. Difficult to be discovered as may not produce a reaction that is noticeable (unreported) Increase in # of meds taken = increase risk of drug interaction. 60% of seniors take 5+ drugs (high risk for drug interaction) Make a drug less effective treat(cid:373)e(cid:374)t failure (cid:894)i(cid:374)crease (cid:374)egative sy(cid:373)pto(cid:373)s(cid:895) Drug interactions can be intended (can be used to eliminate a certain drug) Over the counter drug is more likely to have drug interactions since you are bypassing the physician. So they are not able to warn you for potential drug interactions. Drug nutrient: e. g. monoamine oxidase inhibitor & tyramine in foods = bp (restrict certain food intake) Medical condition can make drug have an increase in harmful effects.
