BCH 2333 Chapter Notes - Chapter 1: Nuclear Magnetic Resonance, Chemical Structure, Copolymer
13 Feb 2014
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Three parts of biochemistry: structural chemistry (components of living matter, metabolism (totality of chemical reactions in living matter, genetic biochemistry (how biological info is stored) leads to molecular genetics (study of heredity and gene expression) Watson and crick proposed the structure of the dna. Human genome has 2. 9 x 10^9 base pairs. Wohler demonstrated that he can create urea without a kidney. X-ray diffraction 3d structure of macromolecules. Nuclear magnetic resonance 3d structure of macromolecules. Biochemistry as a discipline and an interdisciplinary science. It is a mix of many other disciplines organic chem. , physical chem. , thermodynamics, etc. Biological molecules: dna has a mass of 2 billion da, proteins are smaller, about 10000-1 million da, macromolecules (giant molecules, make up large portion of mass of a cell) Polymer: polymers are made of joining monomers through condensation (removal of h2o) Carbohydrate is a polymer (ex. cellulose) which is made of covalently linked monomers, glucose. Cellulose is a polysaccharide because glucose is a saccharide.
