Textbook Notes (363,328)
Canada (158,336)
Biology (653)
BIO152H5 (140)
Chapter 4

Chapter 4- Nucleic acids.docx

2 Pages
Unlock Document

University of Toronto Mississauga
Fiona Rawle

Chapter 4- Nucleic Acids and the RNAWorld Metabolism: The ability to acquire particular molecules and use them in controlled chemical reactions that maintain conditions suitable for life and that contribute to growth. -Nucleic acid- monomer- nucleotides. 1. Aphosphate group 2.Asugar 3. Nitrogenous base. Phosphate is bonded to sugar molecule which is bonded to nitrogenous base. -Sugar: Organic compound with a carbonyl group (C=O) and several hydroxyl (OH) groups. -Ribose has an –OH group bonded to the second carbon. Deoxyribose has an H instead at the same location. -Purines: adenine, guanine -Pyrimidines: cytosine and uracil (thymine) -The polymerization reaction involves the formation of a bond between the phosphate group of one nucleotide and the hydroxyl group of the sugar component of another. The result of this condensation reaction is a phosphodiester bond. -The sugar-phosphate spin is directional 5’ 3’ -The addition of one or more phosphate group raises the potential energy of the substrate molecules enough to make an endergonic reaction possible. Phosphorylated nucleotides are activated. DNA Watson &Crick: Double helix, sugar-phosphate backbones outside of spiral and nitrogenous bases on the inside. Complementary base pairing. -DNA’s primary structure serves as a mould or template for the synthesis of a complementary strand. -The lack of a 2’hydroxyl group on deoxyribon
More Less

Related notes for BIO152H5

Log In


Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.