BIOB33H3 Chapter Notes - Chapter 4: Stratum Corneum, Eccrine Sweat Gland, Stratum Granulosum

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11 Oct 2016
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Serves to protect an individual from surrounding environment. Its receptors also tell us about the outside world, and it helps regulate body temperature. Coordination of immune response to pathogens and cancers in skin. Ve layers of keratinocytes in the epidermis in thick skin and four layers in thin skin. Sensory receptors detect touch, pressure, pain, and temperature. Coordinates immune response to pathogens and skin cancers. Four cell types: keratinocytes - most abundant epithelial cells, melanocytes - pigment producing cells, merkel cells - involved in detecting sensations. 4. langerhan cells - phagocytic cells of the immune system. Division of basal cells in the stratum basal produces new keratinocytes, which replace more super cial cells. As new committed epidermal cells differentiate, they pass through the stratum spinosum, the stratum granulosum, the stratum lucid (of thick skin) and the stratum corneum. The keratinocytes move toward the surface, and through the process of keratinization, the cells accumulate large amounts of keratin.

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