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HLTB21H3 (177)
Chapter 12

Chapter 12 study guide

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University of Toronto Scarborough
Health Studies
Caroline Barakat

Plagues and People Chapter 12: The Great Pox Syphilis The men in the Tuskegee Syphilis Study were denied treatment for syphilis even after penicillin came into use in 1947. It came to symbolize racism in medicine, and ethical misconduct in medical research. the great pox as the English called it, was a disease that from 1493, swept over Europe and the rest of the world. Claimed that the disease was brought to Naples by Spanish troops sent to support Alphonso II of Naples against the French king Charles VIII. Charles invaded Italy and troops contracted the Great Pox and forced their withdrawal. French called this pox the disease of Naples blaming the Italians for it, and the Italians called it the French disease Two main theories: Columbian theory and the pre-Columbian theory. Columbian theory: Columbus visited the Americas in 1492, and then went back to Spain take back natives that then joined Charles VIII s army. By the end of the 1800s, the virulence of the pathogen and the number of cases decline. One hypothesis is: a new disease introduced into a nave population that increased the rate of transmission caused the outbreak, and it transformed into a highly virulent disease. Another hypothesis: European syphilis was derived from yaws, and by a mode of direct contact. Another reason: precautions against transmission were not observed, later stages were not associated with earlier and more infectious stages. Treatments: George Sommariva tried mercury for the treatment of the French pox, it was taken in the form of a drink came to be called salivation because the near poisoning with mercury salts produced a lot of saliva. Treatment: guaiacum (holy wood) resin from trees. It was a useless remedy. Evidence of the Columbian theory, lies in the bones and teeth: bone lesionsscrimshaw patterns and saber thickenings on the lower limbs of adults and notched teeth in children. In the Columbian theory view, syphilis would have existed in Europe and Asia in a milder form prior to 1493, but then it changed and became virulent. www.notesolution.com
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