HLTC23H3 Chapter : THE BURDEN OF THE NEUROCOGNITIVE IMPAIRMENT ASSOCIATED WITH PLASMODIUM FALCIPARUM MALARIA IN SUB.docx

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17 Mar 2012
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The burden of the neurocognitive impairment associated with plasmodium falciparum. Malaria causes significant morbidity in terms of neurologic and cognitive impairment. Plasmodium falciparum is responsible for almost all the mortality from malaria and is the only species that appears to directly affect the central nervous system (cns) causing neurologic deficits and cognitive sequelae1 and epilepsy. Literature search to identify the spectrum and frequency of neurocognitive impairment associated with p. falciparum malaria. Definition of neurocognitive sequelae neurocognitive sequelae are defined as impairment of neurologic or cognitive function. The neurologic impairment consists of loss of function in motor, including coordination, speech, vision, and hearing domains and epilepsy. In 2000, 557 million people living in areas of sub-saharan africa climatically suitable for malaria transmission children at risk of developing cerebral malaria (cm), we used estimates of annualized cm from 1191-96. Cm risk - 219,441 person-years exposure to risk among children resident within the hospital"s catchment area between 0 and 9 years old.

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