HMB200H1 Chapter Notes - Chapter 6.2: Psilocybin Mushroom, Psilocybin, Neuroprotection

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24 Mar 2017
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Withdrawal: symptoms that are physiologically & behaviourally opposite the drug"s effects. Opioid: any compound that binds to a group of brain receptors, also sensitive to morphine. Opioid analgesics: drugs that have sleep-inducing (narcotic) and pain-relieving (analgesic) effects. Most powerful pain reliever discovered to date. Fun fact: named after morpheus, the greek god of dreams. Endomorphins (mu receptor: morphine mimics endomorphins, and binds to mu receptors. Found in many regions of the brain & spinal cord & other parts of the body. Synthesized from morphine also bind to mu receptor. More fat-soluble than morphine penetrates bloodstream faster. Creates tolerance and sensitization often leads to overdoses: in order to get the same high must use more and more. Potentially addictive growing cases of prescription abuse. Competitive inhibitors: opioid receptor antagonists block opioids from binding. Psychotropic drugs: stimulants that mainly affect mental activity, motor activity, arousal, perception, and mood. Psychedelic & hallucinogenic stimulants perception & produce hallucinations.

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