HMB200H1 Chapter Notes - Chapter 2: Cell Migration, Schwann Cell, Astrocyte
Document Summary
Chapter 2: neurons and glia. Franz nissl (german neurologists) 1900s: introduced a stain used today still. Santiago ramon y cajal (histologist) 1888: learned about. Golgi and cajal drew completely opposite conclusions about neurons. Cajal argued that the neuritis of different neurons are not continuous with one another and must communicate by contact, not continuity. The idea that the neuron adhered to the cell theory = neuron. If protein is destined to be inserted into the membrane of a cell/organelle synthesized in the rough er. Neurons are so endowed with rough er because special membrane proteins are what gives them their information- processing abilities. When a mitochondria inhales, it pulls in pyruvic acid and oxygen (floating in cytosol) Pyruvic acid enters the krebs cycle yields atp. When mitochondrion exhales, 17 atp molecules are released for every molecule of pyruvic acid. Pathological changes in axonal map (called tau) have been implicated in the dementia that accompanies.
