PSL301H1 Chapter Notes -Cytotoxic T Cell, Mhc Class I, Antigen-Presenting Cell
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PSL301H1 Full Course Notes
Verified Note
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Document Summary
Aquired immunity cont"d (818-824: antibody functions, antibody binds to antigen first. Fc region of antibody-antigen complex to bind to fc receptors on an immune cell. A single fc receptor eliminates need for immune cells to have multiple different receptors that recognize different antigens. Immune cells are activated by any antibody-bound antigen. If immune cell is a phagocyte, fc binding initiates phagocytosis, in which antibodies perform the following: act as opsonins, make antigens clump. If immune cell is a nk cell or esinophil fc binding: activates cytotoxic cell responses, release chemicals that destroy antibody-bound antigen, nonspecific response of cytotoxic cells to antibody binding is called antibody-dependent cell-mediated cytotoxicity. Inactivating bacterial toxins: antibodies bind to and neutralize some toxins, when developing vaccines, it trigger antibody production without causing symptoms of disease. Activating mast cells: have ige antibodies attached to their surface, when antigens or complement proteins bind to ige, mast cells degranulate, releasing chemicals that mediate inflammatory response.
