October 24 - Ventricles & Meninges.docx

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Anatomy and Cell Biology
Anatomy and Cell Biology 3319

October 24, 2013 Ventricles & Meninges Pp. 381-383, 407-411 Ventricles of the Brain - Ventricles are expansions of the brain’s central cavity, filled with CSF and lined by epindymal cells - They are continuous with one another and the central canal of the spinal cord - Have paired lateral ventricles that lie in the cerebral hemispheres o Horseshoe shape - Third ventricle lies in the diencephalon o Anteriorly it connects to each lateral ventricle through an interventricular foramen - Fourth ventricle lies in the brain stem o Dorsal to the pons o Superior half of the medulla oblongata o Caudally connects to the central canal o 3 openings occur in the walls:  Paired lateral apertures in side walls  Median aperture in its roof  The holes connect the ventricles to subarachnoid space – allows CSF to fill both the ventricles and subarachnoid space Protection of the Brain - Continuation of meninges - CSF - Blood-brain barrier: protects brain from harmful substances in the blood Meninges - Dura mater surrounding the brain is a two-layered sheet of fibrous connective tissue o Periosteal layer: more superficial and attaches to the internal surface of the skull bones o Meningeal layer: deeper and forms the true external covering of the brain and is continuous with the dura mater surrounding the spinal cord o These 2 layers are fused together, except where they separate to enclose the blood-filled dural sinuses  These sinuses collect blood from the brain and conduct it to the large internal jugular veins of the neck  Largest dural sinus is the superior sagittal sinus in the superior midline - Arachnoid mater forms knoblike projections called arachnoid granulations/villi o These villi project superiorly through the dura mater into the superior sagittal sinus and into some other dural sinuses as well o The villi act as valves that allow CSF to pass from the subarachnoid space into the dural blood sinuses - Pia mater clings tightly to the brain surface, following the contours of the gyri, sulci, and fissures - In several places, the brain’s dura mater extends inward to form flat
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