Biochemistry 2280A Chapter Notes - Chapter 20: Apoptosis, Mutation Rate, Mitosis
1 Jan 2017
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Cancer: one of the major causes of death: arises from violations of basic rules of social cell behavior, cancer is result of having tissues that can renew and repair themselves mechanisms controlling this can go wrong. No significant harm is done if a single cell misbehaves. Breakdown of order when a single cell suffers a genetic alteration that allows it to survive and divide when it should not produces daughter cells that behave the same way. Abnormal cells disrupt the organization of the issue = Cancer cells and their progenies properties": proliferate in defiance of the normal constraints. Invade and colonize territories normally reserved for other cells: = socially deviant features. Cells that have the first property but not the second proliferate excessively but remain clustered together in a single mass = tumor: tumor is benign. Tumor is cancerous only if the cells have the ability to invade surrounding tissue = malignant.
