Biology 2581B Chapter Notes - Chapter 7: Ribonucleotide, Phosphodiester Bond, Gene Expression
28 Mar 2016
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Central dogma (f. crick 1957): dna rna protein: once informaion has passed to protein, can"t get out again, geneic info lows through two stages: transcripion and translaion (involves ribosomes. Protein + rrna, geneic code and trnas: not all dna transcribed into rna is translated to proteins (rrna and trnas) 5" end of the mrna (5" end of the gene where translaion will begin: rna polymerase catalyzes the formaion of a phosphodiester bond b/w irst two ribonucleoides, then sigma falls of and end of iniiaion. 2: eukaryotes primary transcript undergoes ediing. Methyl transferase adds methyl groups to the backwards g and to 1+ succeeding nucleoides in the rna methylated cap. Rough edged sphere with outer envelope enclosing protein matrix. Inside core is enzyme-studded genome: two idenical single strands of rna with many molecules of dna polymerase: reverse transcriptase. During infecion, aids virus binds and injects core into cells of human immune system.
