Biology 1001A Chapter Notes - Chapter 10,11: Sex Linkage, Barr Body, Quantitative Trait Locus
27 Oct 2017
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Sickle cell disease develops when a person has received 2 copies of one gene (one from each parent) that codes for an altered subunit of hemoglobin. Me(cid:374)del"s (cid:373)ost i(cid:373)porta(cid:374)t i(cid:374)(cid:374)o(cid:448)atio(cid:374) -> quantitative approach to science: used statistical analysis in an era when qualitative, purely descriptive science was the accepted practice, mendel chose true- breeding garden peas for his experiments. Cycle 5: mendelian genetics: passed traits without change from one generation to the next, mendel first worked with single-character crosses. P generation: plants used in the initial cross. F1 generation: the first generation of offspring from the cross (f= filial; filius = son: plants in f1 all formed purple flowers -> no evidence of blending with white flowers. F2 generation: second generation of offspring: from self-producing sees, both purple and white flowers produced, me(cid:374)del"s si(cid:374)gle character crosses led hi(cid:373) to propose the principle of segregation. Homozygote state of possessing 2 copies of the same allele.
