Biology 1001A Chapter Notes - Chapter 11.2: Chromatin, Wild Type, Barr Body

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Sex-linked genes genes located on sex chromosomes; inherited differently in males + females. Autosomes chromosomes other than sex chromosomes; genes on these autosomes have sae patterns of inheritance in both sexes. Humans: chromosomes 1-22 are autosomes: females are xx and males are xy in both humans & fruit flies. Y in males has short homology w/ x, allowing them to pair in meiosis: human sex determination depends on the sry gene. Sry (sex determining region of the y) one gene carried on the y chromosome that appears to be the master switch that directs development toward maleness at an early point in embryonic development. After 6-8 weeks as embryo, sry gene becomes active in xy embryos, producing protein that regulates expression of testes. Xx embryos no sry gene causes development of female reproductive structures. Male structures degenerate in xx embryos b/c hormones release by developing testes in xy embryos are nit resent.

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