Biology 1001A Chapter Notes - Chapter 12: Cidofovir, Primase, Telomere
24 Mar 2016
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12. 2a watson and crick"s info to make the model: Each nucleotide has 5 carbon sugars deoxyribose, phosphate group and one of the 4 nitrogen bases: adenine, thymine, cytosine and guanine. Pyrimidines: thymine and cytosine single carbon ring. Purines: adenine and guanine fused ring of nitrogen and carbon (aunt gertrude is pure) Chargaff"s rules: # guanine = # cytosine. Polynucletide chain: nucleotides come together to form this. Sugar phosphate backbone: deoxyribose sugars linked by phosphate groups, sugar- phosphate-sugar-phosphate pattern. Phosphate acts as bridge between 3" deoxyribose sugar and 5" deoxyribose sugar. 3" carbon end has a hydroxyl group that attaches to phosphate. Watson and crick used a lot of h. f. wilkins and franklin research. X ray diffraction: to study the structure of dna, crystal produces light, light reflects off structure. 12. 2b the new model proposed that two polynucleotide chains wind into a double helix. Two sugar backbones are separated by space. Complementary base pairing a and t, c and g.
