Biology 1001A Chapter Notes - Chapter 12: Nucleic Acid Double Helix, Polynucleotide, Deoxyribose

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27 Dec 2015
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12. 2a watson and crick brought together information from several sources to. Dna contains 4 different nucleotides: consists of 5-carbon sugar deoxyribose, phosphate group (5") and one of 4 nitrogenous bases: a, g, t, c. Purines (double carbon ring: adenine and guanine. Pyrimidines (single carbon ring: thymine and cytosine. Dna contains nucleotides joined to form a polynucleotide chain: deoxyribose sugars are linked by phosphate groups in an alternating sugar- phosphate-sugar-phosphate pattern called sugar phosphate backbone. 12. 2b: the new model proposed that two polynucleotide chains wind into a dna. Dna is antiparallel opposite polarity, strands run in opposite direction. Double helix model: the two sugar-phosphate backbones are separated from each other by a regular distance, bases extend into/fill this space. Purine and pyrimidine when paired are wide enough to fill space between backbone chains in double helix (purine/purine too wide, pyrimidine/pyrimidine too narrow) 3" carbon is front, 5" carbon is the back.

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