Biology 1201A Chapter Notes - Chapter 43: Pattern Recognition Receptor, Innate Immune System, Adaptive Immune System
15 Jul 2015
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Why it matters: 1796 dr. edward jenner: Used cowpox to prevent smallpox from occurring - > vaccination. Immune system: natural protection that is our main defense against infectious disease. 43. 1b immune system protect the body: innate immune system: inflammation- creates internal conditions that inhibit or kill many pathogens; specialized cells- engulf or kill pathogens or infected body cells. Relies on germ-line-encoded receptors that recognize a set of highly conserved molecular patterns that are present on the surface of pathogens but not found on host cells. Non-specific: target invading pathogen & has no memory of prior exposure to specific pathogen: adaptive (acquired) immunity: specific- recognizes individual pathogens & mounts an attack that directly neutralizes or eliminates them. Body retains a memory of first exposure so if same pathogen is encountered in future, responds more quickly: immune response: innate & adaptive immunity. I. e. fruit fly: not all cause negative effects; some positive
