Biology 1225 Chapter Notes - Chapter 8: Dna Replication, Cancer, Noncoding Dna
29 Mar 2018
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Cell division is dependent on gene expression. Checkpoints ensure dna has been duplicated correctly. Checkpoints can mutate so its protein products do not work properly. Oncogene helps transform normal cell to mutation -> can be passed to offspring. Checkpoint genes that inhibit mitosis are called tumor suppressors -> tumors form when they are missing. Balance of metabolism is shifted: heavy reliance on atp rather than aerobic respiration. Altered/missing proteins can impair function of plasma membrane. Metastasis: process in which malignant neoplasm spread from one part of. Cancer: disease that occurs when a malignant neoplasm physically and functionally disrupts body to another body tissues, abnormally dividing cells. Mutations at multiple checkpoints are required to make malignant ones -> takes a long time. Neoplasms form when cell loses control of cell cycle and start dividing abnormally. Telomere: non-coding dna sequences that occur at end of eukaryotic chromosomes. Vertebrae telomere: short, non-coding dna sequence repeated thousands of times.
