Pathology 3240A Chapter 12: Pediatric Disorders - Walsh

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Describe the differences between transcervical and transplacental perinatal infections. Outline the pathogenesis and treatment of the respiratory distress syndrome. Define sids an dlist factor sassociated with increased risk. Compare and contrast the terms heterotopia, hamartoma, and teratoma, and provide examples of each. List common benign and malignant pediatric neoplasms and contrast sites of involvement. 2 routes of infection: transcervical (ascending/giving birth, transplacental (hematologically) - infectious agents infect the fetus by passing through the placenta. Common infections are: bacteria (e. g. beta hemolytic strep, viral (e. g. herpes) Fetus acquires a transcervical infection either by: Inhaling infected amniotic fluid into lungs, or: acquiring infection when passing through infected birth canal during delivery. Associated with inflammations: chorioamnionitis = inflammation of the placental membrane, funisitis = inflammation of the umbilical cord. Inflammation is a problem for 2 reasons: 1. Inflammatory cells sit on the membrane and cause narrowing of the amniotic sac membrane, which can lead to direct rupture: 2.

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