Psychology 2220A/B Chapter : Ch 11 - Drug Addiction and Reward

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Lecture 11 drug, drug addiction and reward (ch 15, 15. 1-15. 3) Psychoactive drugs: drugs that influence subjective experience and behavior by acting on the nervous system. Drug administration and absorption: oral ingestion: dissolves in stomach and carried t intestine, and bloodstream, or readily pass through the stomach wall (alcohol) This directness leaves little time to correct an overdose or impurity. Inhalation: drugs absorbed into bloodstream through capillaries in lungs: absorption: through mucous membranes of the nose, mouth and rectum. Once a drug enters the bloodstream, its carried to the cns. Blood-brain barrier helps to prevent dangerous blood borne chemicals to pass from the blood vessels of the. May influence synthesis, transport, release or deactivation of particular neurotransmitters. Drug metabolism: converts drug from active from to non active form. Drug tolerance: shift in the dose-response curve to the right. Tolerant individuals receive less effect from same dosage. Greater dose is required to produce same effect.

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