BI110 Chapter Notes - Chapter 20: Steroid Hormone Receptor, Dna-Binding Domain, Cell Signaling
Document Summary
Molecular signals received by that have receptors tuned to specific signals. When signal molecule binds to receptor cellular response. Changes in gene expression protein synthesis. Gap junctions (animal cells): spread of electrical signals between cells in cardiac muscle. Cell adhesion molecules: integral membrane proteins that bind cells to one another or to extracellular matrix. Specific fit, just like an enzyme binding substrate. Induces molecule change in the receptor that activates its cytoplasmic end. Receptors allow only specific ligands to bind and signal to a cell. Hormone binding domain and dna binding domain. Steroid hormones can pass through lipid bilayer. Hormone binds to its receptor within cytoplasm. Hormone receptor complex can enter nucleus and influence gene expression. Once a quorum (threshold) density of salmonella cells is reached, these bacteria signal each other to increase growth and virulence. Part of protein that can catalyze a reaction. Two proteins interact closely together when ligand is present.
