BIOL 1000 Chapter 4: Eucaryotic cells

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What items need to get in & out of the nucleus: enzymes in, rna out specific protein that take things in & out. Ions in: proteins in/out, mrna, rrna out transcription factors - in import signal sequence proteins must have import or export sequence that tells it what to do if mutated won"t work. The nucleolus (p 35-36: a non-membrane bound inside the nucleus, structure made up of proteins & nucleic acids, ribosomal rna (rrna) is transcribed & assembled w/in the nucleolus. Nuclear lamina: found inside the nucleus under the double membrane, provides structural support mesh like (protein filaments, to further protect dna) Chromatin (p 35: dna plus associated proteins (histone & non-histone proteins) Loosely packed dna -> genes active & transcription occurring. Densely packed dna -> genes inactive & transcription not occurring. Proteins associated w/ dna that are not histones.

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