BIOL 1000 Chapter Notes - Chapter 12: Dna Replication, Complementary Dna, Nitrogenous Base
Document Summary
3) and 3" end (hydroxyl oh-) phosphate of one and 3" hydroxyl of another) Proteins that stabilize the separated strands and prevent re-binding. Works ahead of the replication fork to break and straighten dna, as well as prevent twisting. Build an rna primer so dna polymerase can build nucleotides. Leading strand: adds nucleotides to 3"end of the rna primer in the 5" 3". Lagging strand: adds nucleotides to 3"end of an okazaki fragment"s rna primer in 5" 3" until it reaches the 5" of another rna primer of another okazaki. Removes rna primer on a synthesized okazaki fragment using its 5" 3" exonuclease activity, and replaces it with dna nucleotides using its 5" 3" polymerization activity. Seals okazaki fragment"s together with a covalent bond. A protein that binds behind polymerase and encloses dna, holding the template strand it the polymerase together making replication more efficient.
