BIOL 1000 Chapter Notes - Chapter 5: Transmembrane Protein, Lipid Bilayer, Adenylyl Cyclase

• School: York University
• Department: Biology
• Course: BIOL 1000
• Professor: Nicole Nivillac

Document Summary

75% proteins and 25% phospholipids in mitochondria membrane. Integral -- > interacts with hydrophobic and hydrophilic. Peripheral does not interact with these molecules ^ Main function to allow things to pass through -> molecules/signals. Difference: different percentage of proteins and phospholipids (almost 50% difference) Green proteins do not interacts with hydrophobic regions whereas the integral ones interact. Non polar region will become embedded with the hydrophobic portion important. Difference between monotopic and polytopic is that they have 2 grey parts: one interacts with - Peripheral are found inside a cell do not interact with hydrophobic core part at all! Polar: like water (hydrophilic) non-polar: do not like water (hydrophobic) Their side chains make them polar and non-polar. Taking out integral protein, will change the membrane entirely one portion of the bilayer monotopic. Polytopic covers the entire layer (transmembrane protein) cuz it transmembranes the entire membrane green coils are transmembrane protein integral membrane protein.