BIOL 2021 Chapter Notes - Chapter 16.5: Neuromuscular Junction, T-Tubule, Sarcomere

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Sarcomere Structure
- Sarcomere: one contractile unit inside a myofibril
o Made up of thin actin filaments (light bands) and thick myosin
filaments (dark band)
o Actin’s plus ends are attached to Z discs at each end of the
sarcomere
o The M line (midline) is where myosin molecules are
linked together
o Contraction is the sliding of myosin against actin
o Nothing shortens except the entire sarcomere itself
(actin and myosin stay the same length)
o Don’t need to know accessory proteins
- Neuromuscular junction: nerve cell
contacts the muscle cell
o An action potential causes a
synapse, which causes another
action potential in the muscle cell
- Sarcoplasmic reticulum: (sarco =
muscle) the ER in muscle cells that is
responsible for storing calcium
- T tubules are extensions of the PM
(continuous with PM)
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