KINE 2011 Chapter Notes - Chapter 8.4: Neutrophil Extracellular Traps, Mast Cell, Phagocyte
6 Jan 2018
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Eosinophils: attack parasitic worms; important in allergic rxn, killing of antibody coated parasites through release of granule contents. Increase in circulating eosinophils (eosinophilia) is associated with: Allergic conditions such as asthma & hay fever. Internal parasite infestations, such as worms- attach to worms & secrete substances to kill it. Can also prevent clotting of blood samples drawing for chemical analysis. The blood: mononuclear cells: mononuclear (single nucleus) agranulocytes (cells lacking granules) Monocytes: phagocytosis, antigen presentation, cytokine production & cytotoxicity, emerge from bone marrow while still immature; circulate for 1-2 days; settle down in various tissues. When settled, monocytes mature & enlarge in resident tissues & become known as macrophages: mature monocytes are macrophages, macrophages are large phagocytic cell found stationary in tissues or as mobile white blood sites of infection. They"re a type of white (cid:271)lood (cid:272)ell that e(cid:374)gulfs & digests (cid:272)ellular de(cid:271)ris, foreig(cid:374) substances: macrophages: large eater. Life span can range from several months to years.
