PSYC 3140 Chapter Notes - Chapter 7: Major Depressive Disorder, Prefrontal Cortex, Anhedonia

• School: York University
• Department: Psychology
• Course: PSYC 3140
• Professor: Peter Papadogiannis

Document Summary

Unipolar depression is a disorder in which people only experience depression. Bipolar is where people experience both depressive and manic states. Emotional: sad, no pleasure (anhedonia), anxiety, anger, worry, agitation. Lack of drive, initiative, spontaneity, don"t want to do anything or go anywhere. Behavioural: less active, less productive, move and speak slowly. Cognitive: negative views of oneself, inferiority, less desirable, self-blame. Physical: headaches, indigestion, constipation, dizzy spells, general pain. Major depressive disorder two or more weeks marked by at least 5 symptoms of depression. Peripartum - during pregnancy or within 4 weeks of giving birth. Premenstrual dysphroic disorder clinical depression in weeks prior to menstruation. Endogenous depression is a response to internal factors. Biological: genetic: family, twin, adoption and molecular biological studies. May be tied to genes and chromosomes (5-htt) o. Norepinephrine and serotonin (low activity of two neurotransmitters) Stress leads to poor functioning of immune system. Lower lymphocyte activity, increased crp (c-reactive protein), body inflammation in depressed people.