PSC 431 Chapter Notes - Chapter 1: Cryptococcosis, Transdermal Patch, Portal Venous System
17 Feb 2019
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Pharmacokinetics: pharmacokinetics examines the movement of a drug over time through the body. Most drugs absorbed from the gi tract enter the portal. Sublingual: diffuse into the capillary network and, therefore, enters the systemic. Parenteral administration is used for drugs that are poorly absorbed from the gi tract, and. Parenteral administration is also used for treatment of unconscious patients, and under. Rectal: 50 % of the drainage of the rectal region bypasses the portal circulation, thus, the. The three major parenteral routes are intravascular, intramuscular and subcutaneous. Intravascular: intravenous (iv) injection is the most common parenteral route. This route: enteral circulation and encounter the liver before they are distributed into the general circulation. First pass metabolism by the intestine or liver limits the efficacy of many drugs when taken orally. The abused drug, cocaine, is generally taken by sniffing. For example, amphotericin b is used in treating cryptococcal meningitis. drugs to the skin, usually via a transdermal patch.
