CHE 101 Chapter Notes - Chapter 16: Ketone, Reagent, Iodoform
Document Summary
Preparation of aldehydes: oxidation of primary alcohols. Preparation of ketones: oxidation of secondary alcohols, with organometallics. Reactions of aldehydes and ketones: aldol condensation. Aldehydes and ketones having alpha hydrogen atom: cannizzaro reaction: Aldehydes and ketones having no alpha hydrogen atom: When two carbonyl groups are present within a molecule, think of intramolecular reaction. In this case, it is right >c=0 group: formation of keto esters. Esters having a-hydrogen on treatment with a strong base e. g. c 2 h 5 ona. This reaction is claisen condensation: reformatsky reaction. This is the reaction of a-haloester, usually an a-bromoester with an aldehyde or ketone in the presence of zinc metal to produce b-hydroxyester: pinacol-pinacolone rearrangement. The acid catalysed rearrangement of 1,2 diols (vicinal diols) to aldehydes or ketones with the elimination of water is known as pinacol pinacolone rearrangement: wittig-ylide reaction. Aldehydes and ketones react with phosphorus ylides to yield alkenes and triphenyl phosphine oxide.
