BIO 101 Chapter Notes - Chapter 9: Spindle Apparatus, Sister Chromatids, Dna Replication

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Cell division: process by which a cell repod. Intself: fundamental feature of life, imp. for normal growth, dvlpmnt. , & repair of body (an org. ) Sister chromatids: 2 identical dna molec. s that make up a duplicated chrom. Centromere: specialized region of a chrom. Where sister chromatids: joined, critical for proper alignment & separation of sister chromatids during mitosis. Microtubules: hollow protein fibers, key components of cytoskeleton & make up fibers of mitotic spindle. Kinetochore: proteins @ centromere, provide an attachment point for microtubules of mitotic spindle. Mutation: change in nucleotide seq. of dna. Ordered seq of stages that a cell goes through in order to divide during its live: stages: prepatory phases (g1, s, g2) & division phases (mitosis & cytokinesis) Interphase: stage of cc in which cells spend most of their time, preparing for cd, each chrom. Replicates in s phase resulting in 2 sister chromatids connected @centromere: chrom. s: loosely garthered in nucleus, three distinct sub phases (g1, s, g2)