BIOL 4246 Chapter : 6 21 12
Document Summary
Translational termination- specific process, if you did not have a recognizable stop codon you won"t terminate. Rf1/rf2 and rf3- rf1 or rf2 binds with the help of rf3. No trna binds the a site unassisted by a protein. Programmed dna rearrangements regulationbefore gene expression, not mutations- it i genetically programmed that they can make these changes in the dna. Slipped strand mispairing- triplet repeats cause problems when the reader slips. Multiple sigma factors- most heavily regulated step is initiation of transcription. Anti-sigmas can sequester the sigmas away from the rna pol, so this mechanism is all about sigma availability. The polymerase only transcribes the promoter recognized by the sigma. Regulatory proteins- proteins which bind the dna to regulate initiation of transcription, control whether or not it occurs. Bind the dna until the on/off switch is compressed turning the dna binding on or off. Activators-increase rate of transcription, can also act as repressors.
