BIOL 4246 Chapter : 6 15 12
Document Summary
Subunits- the rna pol does a lot of crap, multisubunited fairly complex enzyme. Sigma subunits program the rna pol to recognize certain promoter sequences. There is a promoter sequence for each sigms. Whan that sigms is on rna pol it can bind the specific sequence and begin transcription. You can control which genes are transcribed by controlling which sigma subunits are available. The core is what actually does the transcribing. Rna pol would bind the dna< scan it looking for the promoter sequence. Then it will form the closed complex then the open complex and it will begin initiation of the transcription of rna> Rna pol had to either release the rna and start again- abortive intiation. Or rna pol had to release the promoter and elongate, physically stretching it out. You don"t need sigma any longer at the onset of elongation.
