01:146:356 Chapter Notes - Chapter 5: Intestinal Epithelium, Eion, Molality
23 Mar 2016
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Chapter five: membrane dynamics: mass balance and homeostasis. Total amount or load of substance: intake + production excretion metabolism. Excretion: elimination of material from the body, usually though urine, feces, lungs, or skin: any foreign substance is called a xenobiotic. Metabolism: converts the original nutrient to a different substance but also creates a new mass balance disturbance by adding more of the metabolite to the body: the product created is called a metabolite. Hepatocytes or liver cells metabolize different molecules that are excreted [skin, sweat, milk, hair: lungs clear volatile lipid soluble materials ethanol, garlic. Clearance: volume of blood plasma cleared of substance x per time: more clear way to measure substance elimination is mass flow. Mass flow (x/min) = concentration (x/vol) x vol flow (vol/min) Na, hco3-, cl more concentrated in ecf; k and large a in icf; ca in ecf a is absent from interstitial fluid.
