01:146:356 Chapter Notes - Chapter 6: Bordetella, Parathyroid Gland, Rhodopsin
23 Mar 2016
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Chapter 6: communication, integration, and homeostasis: cell to cell communication. Cells that receive chemical or electrical signals are called target cells. Four basic methods of communication: gap junctions, which allow cytoplasmic transfer of signals between adjacent cells. Forms from connexons that open and close; when open, the pair acts as a single cell with multiple nuclei (syncytium) Ions, small molecules (amino acids, atp, camp) diffuse directly but large molecules cannot. Gap junctions are the only means by which electrical signals can pass directly from cell to cell. 20 different isoforms of connexin, dependent on what cell is being looked at: contact-dependent signals, which occur when surface molecules on one membrane bind to those on another cell"s membrane. Immune system, growth and development nerve cells send out long extensions that must grow to distal ends of limbs. Cams act as receptors in cell to cell signaling in cytoskeleton and ic enzymes: local communication by chemicals that diffuse through ecf.
