01:694:301 Chapter Notes - Chapter 8: Hydrolysis, Serine Protease, Non-Covalent Interactions
11 Mar 2016
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Catalyst substance that increases the rate, or velocity, of a chemical reaction without itself being changed in the overall process. Substrate substance that is acted on by an enzyme. Trypsin catalyzes hydrolysis of peptide bonds in proteins and polypeptides: trypsin is the enzyme and the polypeptides are the natural substrates for trypsin. Catalysts are unchanged in the reaction process. Catalysts change rates of processes but do not affect the thermodynamic favorability of a reaction: the equilibrium state is just approached more quickly in the presence of a catalyst. 8. 3 chemical reaction rates and the effects of. If n and m = 1, then k1 and k-1 are the rate constants for the first- order forward and reverse reactions. K = [b] / [a] = k1/k-1. First-order in [a] and first-order in [b], but second-order overall: overall order: n + m = 2 (second-order reaction, enzyme-substrate complex.
