KINS 1224 Chapter Notes - Chapter 18: Kernicterus, Fibrinolysis, Histamine

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16 Feb 2017
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Protection inflammation, which limits spread of infection. White blood cells destroy microorganisms and cancer cells. Platelets initiate blood clotting antibodies and blood proteins neutralize toxins and destroy pathogens. Plasma- matrix, over half of blood volume. Mixture of water, proteins, nutrients, electrolytes, wastes, hormones, and gases. Serum- remaining fluid when blood clots and solids are removed; identical to plasma except for the absence of fibrinogen (clotting protein) Protein is the most abundant plasma solute by weight. Transport solutes and buffer ph of plasma. Changes in albumin concentration can affect blood volume, pressure, and flow. Alpha, beta, and gamma (come from plasma cells- connective tissue cells descended from b lymphocytes) Soluble precursor of fibrin, framework of a blood clot. Nitrogenous wastes- toxic end products of catabolism; urea; excreted by kidneys. Sodium ions are 90% of cations (important for osmolarity, blood volume and pressure) People with high bp are told to reduce sodium intake.

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