BIOL 2100 Chapter Notes - Chapter 5.5, 12.1, 12.2: Spindle Apparatus, Sister Chromatids, Nuclear Membrane

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Cell division occurs in prokaryotic and eukaryotic cells when dna is distributed to two daughter cells. Genome = a cell"s endowment of dna. Chromosomes = a package of dna molecules. Each chromosome has one long dna molecule with many proteins associated. Proteins help chromosome maintain shape and regulate genes. Each dna has hundreds to thousands of genes that dictate the organism"s inherited traits. Chromatin = dna and proteins that make up chromosome. Chromosomes only condense when the cell is dividing. Each duplicated chromosome has two sister chromatids. Centromere = region in chromosomal dna where sister chromatids are most closely attached. Mitosis = division of genetic material in nucleus. Flemming observed chromosome division for the first time. Mitotic spindle = fibers made of microtubules. Kinetochore = specialized protein structure at centromere. Nonkinetochore microtubules interact with those on the opposite side of the spindle. Centrosomes at opposite poles of the cell. Chromosomes line up on the metaphase plate.

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