BIOL10005 Lecture Notes - Lecture 9: Non-Coding Rna, Stem-Loop, Sister Chromatids

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Recombination is when there is an exchange in genetic material between homologous pair but not between the sister chromatids. Gametes that stay the same -> non recombinants. The further the two locus are from each other, the higher the frequency of recombination. If ratio of the phenotypes in the offspring after test cross of a heterozygote is different from 1:1:1:1 -> linked genes. Genes that are 50mu apart will assort independently. Consists of regulatory sequence and coding sequence. Non-coding strand is the template strand -> same as mrna except for uracil instead of thymine. Unwinds dna and starts to produce complementary rna. T(cid:396)a(cid:374)s(cid:272)(cid:396)iptio(cid:374) (cid:271)egi(cid:374)s at (cid:858)+(cid:1005) (cid:396)egio(cid:374)(cid:859) o(cid:396) (cid:858)do(cid:449)(cid:374)st(cid:396)ea(cid:373)(cid:859) Na poly(cid:373)e(cid:396)ase (cid:373)o(cid:448)es f(cid:396)o(cid:373) 5(cid:859) to (cid:1007)(cid:859) to u(cid:374)(cid:449)i(cid:374)d, a(cid:374)d (cid:396)e(cid:449)i(cid:374)ds the p(cid:396)e(cid:448)ious (cid:396)egio(cid:374)s. Rna polymerase adds rna nucleotides to the new forming strand: termination. Secondary structure called hairpin loop is formed. Uracil instead of thymine: types of rna. Mirna rrna (catalytic & structural role) trna snrna (splicing)

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