HUBS1403 Lecture 19: week 8

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Does not synthesize hormones stores and releases from axon terminals two hormones produced by neurosecretory cells of the hypothalamus: Anterior pituitary gland secretes 7 hormones produced by 5 different types of cells. Negative feedback loops control the secretions of thyrotrophs, gonadotrophs and corticotrophs. Hormones of the anterior pituitary released in bursts every few hours by somatotrophs: human growth hormone (hgh) Most plentiful anterior pituitary hormone: somatotroph activity controlled by two hypothalamic hormones: growth hormone-releasing hormone (ghrh) growth hormone-inhibiting hormone (ghih). Butterfly-shaped gland located inferior to the larynx and anterior to the trachea. right and left lateral lobes connected by an isthmus. Tsh drives follicle cell production of thyroid hormones (t4 & t3) that stimulate cellular metabolism throughout the body. T4 = thyroxine = tetraiodothyonine (major thyroid hormone) Follicular cells are stimulated by tsh to produce the thyroid hormones thyroxine (tetraiodothyronine, t4) triiodothyronine (t3) . Parafollicular cells produce the hormone calcitonin to help regulate calcium homeostasis.

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