HUBS1404 Lecture Notes - Lecture 12: Breathing, Peripheral Chemoreceptors, Cellular Respiration
19 Jul 2018
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Document Summary
The oxygen requires for oxidative metabolism by exercising muscle travels from the atmosphere to the muscle mitochondria in 3 distinct steps. During heavy exercise, large muscles can increase their. The start of exercise is characterised by an immediate increase in ventilation. Initial increase is probably mediated by anticipation of future need (recall that higher brain regions modulate respiratory centres) Subsequent increases in ventilation will be driven by a number of respiratory reflexes. 1 of the strongest determinants of ventilation is a change in pco2 and ph as detected by central and peripheral chemoreceptors. Ventilation and oxygen consumption increase with exercise intensity. Diastolic bp decreases (dilation of muscle arteries leads to less resistance)
