BIOL 2P02 Lecture Notes - Lecture 26: Rna Splicing, Intron, Polyadenylation

• School: Brock University
• Department: Biological Sciences
• Course: BIOL 2P02
• Professor: Adonis Skandalis

Document Summary

Function of poly(a: protect from degradation. Partially processed: (cid:1009)" e(cid:374)d has a (cid:1011)-methyl g attached to an a. Translation occurs at the exon (protein information: starts at the upstream(utr) exon (transcription start) and moves to the downstream exon (utr) (polyadenylation, partially processed due to the presence of the intron that needs to me removed. Intron removed and thrown out; contains regulatory information but no information regarding protein synthesis: utr is always going to be there in the mature message; no information regarding protein synthesis. Introns are spliced out, exons are spliced in. Splicing happens at the same time as transcription takes place mrna modifications mrna splicing. Figure 16-5: splicing and transcription happen at the same time. Rna is (cid:272)(cid:396)eated, (cid:272)apped at the (cid:1009)" end (beginning of transcription), hits an intron, splices as it gets transcribed, polyadenylation takes place. Figure 16-6: loops are the introns (stuff that needs to be removed, 16-6b outlines exons in green.