BIOL 2P05 Lecture Notes - Lecture 14: Mendelian Inheritance, Methicillin, Erythromycin
10 Feb 2018
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*in smaller populations, genetic drift also results in much higher between population variation, than in larger populations. You grab 2 handfuls of 5 (2 small populations) You grab 2 handfuls of 100 (2 larger population) You grab a bag of 10,000 marbles (0. 5% black) If your handfuls look different --> high between population diversity (each handful is a population) Mrsa has a mutated membrane protein that no longer binds methicillin. This modification is highly beneficial in the presence of antibiotics, but has negative fitness consequences in other environments. Selective pressure increases the presence of this mutation in the presence of antibiotics. In the absence of antibiotics, selection acts against. Mendelian inheritance is compatible with small graded variations. Phenotype of an individual can be determined by adding the effects of each allele. More alleles for dark colour, darker the coffee beans. Not all phenotypes can be represented in one generation.
