BIOL 2P05 Lecture Notes - Lecture 8: Interferon Type I, Sphingidae, Phylogenetic Tree
21 Apr 2018
School
Department
Course
Professor
Document Summary
Bacteria, archaea, eukaryota: organisms to proteins, modern cgas and sting have acquired structural features for dna binding in cgas as well as carboxy terminal tail domain for transducing signals in sting. Induces type i interferon production when cells are infected w/ intracellular pathogens. Sister taxa: more closely related to each other than other taxa in the tree-share recent common ancestor. Polytomy: an internal node having more than two immediate descendants. Clade: group of taxa sharing a common ancestor, monophyletic clade: consists of all descendants and the recent common ancestor. Polyphyletic clade: does not include all common ancestors nor all descendants of that ancestor. Paraphyletic clade: contains most common ancestors but not all the descendants. Phylogram: branch lengths indicate amount of evolutionary change. Do not fully indicate direction of time, tips most recent: midpoint rooting. Find the longest path from tip to tip and find the midpoint. Direction in a rooted tree indicates passage of time.
