BIOL 3P30 Lecture Notes - Lecture 4: Phospholipid, Heat Shock Protein, Lysosome
22 Aug 2015
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Document Summary
Post-translational modifications change the specific activity of proteins. Only change the absolute amount of proteins secondarily (i. e. because transcription factors may also be reversibly phosphorylated and thus activated or inactivated. Autophagy: the process within a cell, involves lysosomes, damaged stuff is recognised and targeted for lysosomes to begin degradation into smaller subunits which can be recycled. Histone deaceylases regulate histone acetylation and thus dna packaging, and thus gene expression. Assembly of the basal transcription complex of dna. Basal transcriptional complex: lots of things come together to built the machine (bunch of proteins all together) Enhancer are accessory proteins which interact with both the dna and the complex. These are proteins that interact with regions of dna and basal complex to change how it works and how fast it works. R is a protein which inhibits transcription of a gene. R binds to the enhancer, but doesn"t interact with the basal factor from binding there doesn"t occur.
